fuchs heterochromic iridocyclitis and pellucid corneal marginal degeneration: a co-incidence or a developmental defect?

purpose: to report a patient with fuchs' heterochromic iridocyclitis and pellucid corneal marginal degeneration. case report: a 37-year-old woman referred to poostchi eye clinic, shiraz, iran with complaint of low vision in both eyes especially in the left side since many years ago. on ophthalmologic examination, best-corrected visual acuity was 20/50 in right eye with refraction of -6.50-7.5@90º and 20/80 in left eye with refraction of -8.50-11.00×90º. slitlamp examination revealed inferior thinning of cornea in both eyes and diffuse keratic precipitates on corneal endothelium, 1+ cell and flare in the anterior chamber and posterior subcapsular cataract in left eye. there was a moderate iris hetererchromia between the eyes which beside other findings was suggestive of fuchs' heterochromic iridocyclitis. corneal topography was in favor of pellucid marginal degeneration. conclusion: to our knowledge this is the first case of pellucid marginal degeneration associated with fuchs' heterochromic iridocyclitis in the literature. this may be a co-incidence or might have occurred due to a defect in embryonic ocular development.